Different methods of 3D QRS area calculation from vectorcardiographic X, Y, and Z Leads.

Abstract

3DQRSarea is a strong marker for cardiac resynchronization therapy and can be obtained by taking the (i) summation or the (ii) difference of the areas subtended by positive and negative deflections in X, Y, Z vectorcardiographic electrocardiogram (ECG) leads. We correlated both methods with the instantaneous-absolute-3D-voltage-time-integral (VTIQRS-3D). 3DQRSarea consistently underestimated the VTIQRS -3D, but the summation method was a closer and more reliable approximation. The dissimilarity was less apparent in left bundle branch block (r2 summation.996vs. difference.972) and biventricular paced ECGs (r2.996vs..957) but was more apparent in normal ECGs (r2.988vs..653).