Abstract
Siddha system of medicine, one of the ancient medical systems has the great potential of medicinal resources as repository since ages. Diabetes is a major lifestyle disorder, the prevalence of which is increasing globally. Diabetes mellitus is compared with Madhumegam in Siddha literature. Most of the contemporary drugs work on insulin metabolism and several metabolic pathways to reduce hyperglycaemic conditions. The conventional Siddha drugs works on the same platform through its basic principles. Siddha medicinal plants which are having hypoglycaemic activity by involving various metabolic pathways are taken in to account and considered for a review. This process will create some new ideas in the avenue of research.
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