Different effects on anemia of short-term indoor air purifier intervention in housewives: KoCHENS-MOM study

Abstract

Background Housewives are involved in daily household chores such as cleaning and laundry, thus making them exposed directly to indoor particulate matter (PM) exposure. Indoor PM exposure is a potential factor that increases systemic inflammation and affects hematopoietic action. This study aims to investigate the association between indoor PM and indicators of anemia (Hemoglobin, Mean Cell Volume; MCV, Mean Corpuscular Hemoglobin; MCH, Mean Morpuscular Hemoglobin Concentration; MCHC, Erythrocyte Sedimentation Rate; ESR) during air purifier intervention in housewives. Methods We recruited a total of 300 housewives in Seoul and Ulsan, Republic of Korea. Among them, we analyzed the data of 40 housewives who were subjected to the Air cleaner arbitration. Indoor exposure level of PM2.5 and PM10 of each housewife was analyzed as the adjusted value of the sensor measurement. We also investigated the indicator of anemia such as hemoglobin, MCV, MCH, MCHC and ESR before and after the installation of air purifier for one month. Statistical analysis was performed by multiple generalized linear model (GLM). Results The difference in indoor PM exposure levels by air purifier was related in all anemia indicators (Hemoglobin, MCV, MCH, MCHC and ESR). The decrease in the level of indoor PM2.5 level was associated with a decrease in MCHC (β: -1.39, P = 0.05) and ESR (β : -0.08, P = 0.04). The decrease in level of indoor PM10 level was associated with a decrease in MCVH (β: -2.60, P = 0.05) and ESR (β: -0.16, P = 0.04). Conclusion Our results suggest, that the intervention of indoor air purifier decreases PM exposure and affects the anemia indicators. In addition, we will analyze the effects of the air purifier for about three months. In conclusion, anemia and inflammation can be improved by managing indoor PM exposure