Different effects of 5-fluorodeoxyuridine and 5-bromodeoxuridine on the frequencies of chromatid aberrations obtained in vicia faba after irradiation with X-rays

Abstract

Results of a studi, on the production of chromosomal aberrations in Vicia faba by 5-fluorodeoxyuridine (fUDR) and by 5-bromodeoxyuridine (BUDR) alone, and in combination with x radiation, indicate that the chromosomal damage obtained after x irradiation may be increased by both FUDR and by BUDR, but that the effects are qualitatively different and are probably produced by different mechanisms.