Abstract

The active form of vitamin D is 1,25 dihydroxy vitamin D. Renal and many extra renal tissues are able to synthesize 1,25 dihydroxy vitamin D on a local and intracellular level. Local tissue level of 1,25 di-hydroxyvitamin D is determined by concentration of circulating 25(OH) vitamin D level. Stroke is a common worldwide health problem. It is a major cause of morbidity, mortality and disability in developed as well as developing countries. Both vitamin D deficiency and stroke are very common in urban and rural India. Hence this study was designed to evaluate the association of vitamin D deficiency in acute stroke. This study shows the different comparison of MEAN SR. HOMOCYSTENE in serum 25 – hydroxyvitamin D in acute stroke and found to be in total serum homocysteine levels were 19.64 micro mole/l in cases than 10.1 in control However the difference was statistically highly significant (p<.0002).

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