Abstract

SummaryIn the enlarged adrenals of renal hypertensive rats there Is a relative increase in medullary size, whereas in the enlarged adrenals of rats treated with ACTH there is a relative decrease in medullary size. Large numbers of PAS positive intracytoplasmic bodies are found in the cortical fascicular zone in the adrenals of rats with severe chronic renal hypertension, but were not produced in comparable numbers with ACTH. It is concluded that factors in addition to ACTH are concerned in the growth of the adrenal in renal hypertension.

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