Abstract
A comparison of the effects of dose-rate on the acute intestinal syndrome measured by animal survival five days after whole-body irradiation and on cell survival of the epithelial cells of the jejunum measured by clone production after local irradiation show a close correlation between the two tests of radiation damage. The greater sensitivity of animals measured by death within five days of irradiation to higher dose-rates is observed at the cellular level also. Irradiation of adjacent segments of jejunum suggest that the dependence of sensitivity on dose-rate is inherent in the cells rather than due to a radiation-induced change in the “environment” of the cells.
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