Differences in response inhibition processes between adolescents and adults are modulated by sensory processes

Abstract

Response inhibition processes undergo strong developmental changes. The same is true for sensory processes, and recent evidence shows that there also within-modality differences in the efficacy to trigger motor response inhibition. Yet, modulatory effects of within-modality differences during age-related changes in response inhibition between adolescence and adulthood are still indeterminate. We investigated this question in a system neurophysiological approach combining analysis of event-related potentials (ERPs) with temporal EEG signal decomposition and source localization processes. We used the somatosensory system to examine possible within-modality differences. The study shows that differences in response inhibition processes between adolescents and adults are modulated by sensory processes. Adolescents show deficient response inhibition when stimuli triggering these mechanisms are processed via SI somatosensory areas, compared to SII somatosensory areas. Opposed to this, no differences between adolescents and adults are evident, when response inhibition processes are triggered via SII cortical regions. The EEG data suggests that specific neurophysiological subprocesses are associated with this. Adolescents seem to encounter problems assigning processing resources to integrate motor with tactile information in posterior parietal areas when this information is processed via SI. Thus, basic perceptual and age-related processes interactively modulate response inhibition as an important instance of cognitive control.