Abstract
BackgroundIn the current surgical therapeutic regimen for the degenerative lumbar disease, both oblique lateral interbody fusion (OLIF) and lateral lumbar interbody fusion (LLIF) are gradually accepted. Thus, the objective of this study is to compare the radiographic and clinical outcomes of OLIF and LLIF for the degenerative lumbar disease.MethodsWe conducted an exhaustive literature search of MEDLINE, EMBASE, and the Cochrane Library to find the relevant studies about OLIF and LLIF for the degenerative lumbar disease. Random-effects model was performed to pool the outcomes about disc height (DH), fusion, operative blood loss, operative time, length of hospital stays, complications, visual analog scale (VAS), and Oswestry disability index (ODI).Results56 studies were included in this study. The two groups of patients had similar changes in terms of DH, operative blood loss, operative time, hospital stay and the fusion rate (over 90%). The OLIF group showed slightly better VAS and ODI scores improvement. The incidence of perioperative complications of OLIF and LLIF was 26.7 and 27.8% respectively. Higher rates of nerve injury and psoas weakness (21.2%) were reported for LLIF, while higher rates of cage subsidence (5.1%), endplate damage (5.2%) and vascular injury (1.7%) were reported for OLIF.ConclusionsThe two groups are similar in terms of radiographic outcomes, operative blood loss, operative time and the length of hospital stay. The OLIF group shows advantages in VAS and ODI scores improvement. Though the incidence of perioperative complications of OLIF and LLIF is similar, the incidence of main complications is significantly different.
Highlights
In the current surgical therapeutic regimen for the degenerative lumbar disease, both oblique lateral interbody fusion (OLIF) and lateral lumbar interbody fusion (LLIF) are gradually accepted
Radiographic and clinical outcomes of LLIF or OLIF have been assessed in many studies, few studies have compared the results of OLIF and LLIF
Studies were eligible for inclusion if they met the following criteria: studies reported outcomes at least one of the following outcomes: disc height (DH), visual analog scale (VAS), Oswestry disability index (ODI), operative blood loss, operative time, length of hospital stay, fusion, and complications; and had sufficient data to extract and pool
Summary
In the current surgical therapeutic regimen for the degenerative lumbar disease, both oblique lateral interbody fusion (OLIF) and lateral lumbar interbody fusion (LLIF) are gradually accepted. The objective of this study is to compare the radiographic and clinical outcomes of OLIF and LLIF for the degenerative lumbar disease. Lumbar interbody fusion has been recognized as a powerful surgical tool for lumbar degenerative disease, including degenerative disc disease, spondylolisthesis, disc herniation, and deformity [1, 2]. Traditional techniques, such as anterior lumbar interbody fusion and posterior/transforaminal lumbar interbody fusion, have. In the present study, considering the increasing interest in these techniques, our meta-analysis is performed to find differences in the radiographic and clinical outcomes of OLIF and LLIF for degenerative lumbar disease and, provide vital evidence-based guidance for clinicians
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