Differences in Physical Activity between Patients with Peripheral Artery Disease and Healthy Subjects.

Sumiko Shiba,Atsutoshi Hatada,Akiko Shiba,Carmela R Balistreri

doi:10.1155/2020/5093528

Sumiko Shiba, Atsutoshi Hatada + Show 2 more

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https://doi.org/10.1155/2020/5093528

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Abstract

Objectives Peripheral artery disease (PAD) is a significant prognostic marker of poor long-term survival due to limited physical activity associated with various functional problems, such as intermittent claudication. A physically active lifestyle has the potential to modify peripheral artery risk factors and promote general health. While low daily physical activity levels have been recognized in the population of PAD, the exact level has yet to be quantified due to lack of research. The aim of the present study was to compare physical activity level (PAL) and time spent at activities of different intensity levels between patients with PAD and healthy individuals. The study subjects were 10 patients with PAD and 10 age-matched healthy control subjects. We measured the time spent at light, moderate, or vigorous physical activity using triaxial accelerometer and calculated PAL. Intermittent claudication onset distance and maximum walking distance were defined as the distance walked at which the subject first reported leg pain and the distance at which the subject was unable to continue walking because of leg pain, respectively. Results Our results showed (i) lower PAL in patients with PAD compared with the controls; (ii) while there was no significant difference in the high-intensity activity between the two groups, the light- and moderate-intensity activities of the PAD group were significantly lower than the controls, the time spent at moderate-intensity activity was approximately 50% less; and (iii) among patients with PAD, low PAL did not correlate directly with intermittent claudication. Conclusions PAD patients limit the amount of their physical activity, especially light and moderate intensities. Our study highlights the importance of spending more time walking in daily life.

Highlights

Peripheral artery disease (PAD) is an atherosclerotic disease known to lead to narrowing of the lower limb arteries
Discussion is study investigated physical activity level (PAL) of patients with PAD using triaxial accelerometer. e main findings were as follows: (i) patients with PAD had lower PAL than the control; (ii) there was no significant difference in the high-intensity activity between the two groups; the light- and moderateintensity activities were significantly less in the PAD group than the control, especially the time spent at moderate-intensity activity was approximately 50% less (40 minutes fewer); and (iii) among patients with PAD, low PAL did not directly correlate with intermittent claudication (IC)
A high cadence level of walking is equivalent to moderate-intensity activity [19], and a moderate cadence level is considered to be equivalent to low-intensity activity. us, it is considered that their study supported our result. e greater differences in our present study are that our subjects are more than 10 years older and that we showed physical activity intensity

Summary

Introduction

Peripheral artery disease (PAD) is an atherosclerotic disease known to lead to narrowing of the lower limb arteries. Previous studies reported that PAD is associated with significant risk of cardiovascular disease morbidity and mortality [1,2,3]. As the primary symptom of PAD, intermittent claudication (IC) appears during physical activity when the blood and oxygen demands of the working skeletal muscle exceed supply. Patients with IC experience functional decline due to the limitation in physical activity, further raising the risk of cardiovascular events in a vascular system already compromised by the underlying atherosclerosis. Physical activity and cardiorespiratory fitness are known to be associated with enhanced health and quality of life, and even small improvement in fitness correlates with reduced cardiovascular and all-cause mortality [4,5,6,7,8]. Erefore, it is important to encourage physical activity to improve health status. While low daily physical activity levels have been recognized in this population, the exact level has yet to be quantified due to lack of research

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