Differences between genders in colorectal morphology on CT colonography using a quantitative approach: a pilot study

Abstract

PurposeTo explore quantitative differences between genders in morphologic colonic metrics and determine metric reproducibility. MethodsQuantitative colonic metrics from 20 male and 20 female CTC datasets were evaluated twice by two readers; all exams were performed after incomplete optical colonoscopy. Intra−/inter-reader reliability was measured with intraclass correlation coefficient (ICC) and concordance correlation coefficient (CCC). ResultsWomen had overall decreased colonic volume, increased tortuosity and compactness and lower sigmoid apex height on CTC compared to men (p<0.0001,all). Quantitative measurements in colonic metrics were highly reproducible (ICC=0.9989 and 0.9970; CCC=0.9945). ConclusionQuantitative morphologic differences between genders can be reproducibility measured.