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Abstract
Objective:To analyze and compare the efficacy of laparoscopic modified Soave operation and open radical resection in the treatment of Hirschsprung’s disease.Methods:Two hundred and sixteen children who suffered from Hirschsprung’s disease and were admitted into the hospital from June 2015 to December 2016 were selected as research subjects. They were grouped into an observation group in which patients were treated by laparoscopic modified Soave operation and open radical resection and a control group in which patients were treated by open radical resection. The clinical efficacy and complications of the two groups were observed, and the defecation function was also evaluated.Results:Operation indicators such as the operation time, time to recovery of intestine peristalsis, intraoperative blood loss and pain score of the observation group were superior to those of the control group, and the difference had statistical significance (P<0.05). The mean arterial pressure (MAP) and heart rate (HR) of the observation group were lower than those of the control group at all time points after operation, and the difference suggested statistical significance (P<0.05). The postoperative complications of the observation group were less than those of the control group. The follow-up results demonstrated that the excellent and good rate of Kelly score of the observation group was 81.5%, higher than 61.1% in the control group.Conclusion:Laparoscopic modified Soave operation has definite efficacy in the treatment of Hirschsprung’s disease, and the treatment is featured by high safety and few complications, which is beneficial to the recovery of defecation function; hence laparoscopic modified Soave operation is worth clinical promotion.
Highlights
Pediatric Hirschsprung’s disease which manifests as repetitive abdominal distention is commonly seen in clinics, and its cause is the lack of ganglion cells in intestinal canal
This study investigated the clinical efficacy of modified Soave operation under the assistance of laparoscope by analyzing the Hirschsprung’s disease patients who were admitted into Binzhou People’s Hospital, Shandong, China, aiming to provide a reference for clinical treatment
It included 187 cases of common type and 29 cases of long-segment type. They were divided into two groups randomly, i.e., an observation group in which patients were treated by laparoscopic modified Soave operation and a control group in which patients were treated by open radical resection
Summary
Pediatric Hirschsprung’s disease which manifests as repetitive abdominal distention is commonly seen in clinics, and its cause is the lack of ganglion cells in intestinal canal. Investigations have suggested that[1,2], the number of Hirschsprung’s disease children who received treatment showed a sustainable growth in recent years, and its morbidity has ranked the second place among various digestive tract abnormality. Soave operation has gained an extensive application in clinics since transanal Soave operation was reported being used for treating Hirschsprung’s disease abroad in 1988. Smith et al initially reported the application of laparoscope in Duhamel megacolon radical operation in 1994.4 Georgenson et al reported the clinical application of laparoscopic Soave operation in the treatment of megacolon.[5]
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