Abstract
Urinary N-acetyl-beta-D-glucosaminidase (NAG) activity differed greatly between male and female beagle dogs in an age-matched group. The NAG activity in males per animal, per body weight, or per 16-hour urine sample was approximately double that in females and was 2.4-fold higher when the activity was considered relative to urinary creatinine. On the other hand, alanine aminopeptidase activity relative to urinary creatinine was not significantly different between males and females. These findings indicate that when using urinary NAG activity to detect drug nephrotoxicity in dogs, some consideration must be given to different control levels between males and females before starting drug administration.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
