Abstract
BackgroundWe sought to determine the difference in the localization of coronary artery disease (CAD) between the left and right coronary artery system and investigate the effect of sex and age on that difference.MethodsWe retrospectively analyzed 17,323 consecutive angiographies from January 1st, 1984 to December 31st, 2003. The demographic parameters, in particular age and sex of the investigated cases as well as the angiographic results were recorded and summarized.ResultsOf 13,305 cases with CAD, 861 (6.5%) had right coronary artery (RCA)-only disease, 4,621 (34.7%) had left coronary artery (LCA)-only disease, while 7,823 (58.8%) cases had concomitant RCA and LCA disease. LCA-only disease was more frequent than RCA-only disease [LCA-only/RCA-only odds ratio (OR): 5.37, 95% CI: 4.99 to 5.77, p < 0.001]. Women were more likely to have LCA-only disease (men/women OR 0.75 95% CI: 0.68 to 0.82, p < 0.001) compared with men who were more likely to present with concomitant RCA and LCA disease (men/women OR 1.33 95% CI: 1.21 to 1.45, p < 0.001). RCA-only and LCA-only disease were both more frequent in patients aged from 51 to 60 years, while concomitant RCA and LCA disease in patients between 61 and 70 years of age.ConclusionsLCA-only disease is more frequent than RCA-only disease. Men have a higher probability than women to present with concomitant RCA and LCA disease while women are more likely than men to be found with LCA-only disease.
Highlights
We sought to determine the difference in the localization of coronary artery disease (CAD) between the left and right coronary artery system and investigate the effect of sex and age on that difference
left coronary artery (LCA)-only disease was more frequent than right coronary artery (RCA)-only disease (LCA-only/RCA-only odds ratio (OR): 5.37, 95% confidence intervals (95% CI): 4.99 to 5.77, p < 0.001)
LCA-only disease was more likely to occur in women than in men
Summary
We sought to determine the difference in the localization of coronary artery disease (CAD) between the left and right coronary artery system and investigate the effect of sex and age on that difference. The above clinical conditions show certain differences in their pharmacologic or interventional management, potential complications as well as patient follow-up In this setting a further investigation of the fre-. The main clinical manifestations of RCA occlusion, isolated right ventricular infarction and isolated left posterior wall infarction, are seen in only a minority of patients presenting with acute coronary syndrome [1,2]. The aim of the present study was to determine the prevalence of CAD in the LCA as compared to the RCA in a large registry of patients referred for coronary angiography to our institution and investigate the effect of sex and age on that prevalence
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