Abstract

1. 1. After a single injection of tritium labelled water (THO) into rabbits the specific activity was measured in blood, urine and evaporative water. 2. 2. The specific activity in urine was similar to that in blood, the specific activity in pulmocutaneous evaporate was 5–8% below that of blood. 3. 3. The permeability coefficient of the urinary bladder wall for THO was 44 ± 11 cm/sec × 10 −6. 4. 4. Maximum differences in the specific activity between blood and urine due to the accumulation of urine in the bladder were calculated as up to 1.8%. 5. 5. In the state of equilibrium the specific activity in urine water, but not in evaporative water. can be used for the estimation of total body water.

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