Abstract
Notwithstanding several attempts<sup>1</sup>in the past to establish a causal relation between diet and the condition of the skin, it is surprising that the possible role of accessory food factors of vitamin-like character has been discussed only to a limited extent in the clinical study of dermatoses.<sup>2</sup>It is equally apparent that the approach to experimental dermatologic research on a nutritional basis has not yet received proper consideration. Of the better known relations between dietary deficiencies and pathologic manifestations of the skin in human beings, those occurring in pellagra<sup>3</sup>should be mentioned first. More recently the syndrome of deficiency of vitamin A with its cutaneous lesions has been the subject of study and is now well recognized.<sup>4</sup> In so far as an experimental basis for clinical observations is concerned, the existence of analogies has been generally ignored between cutaneous manifestations in man and in animals, such
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