Abstract
The study was conducted to assess the effectiveness of a refined sucrose and caffeine free diet in the treatment of depression. Twenty subjects meeting DSM-III-R criteria for a current episode of major depression completed the Beck Depression Inventory (BDI), MMPI-D scale, SCL-90, Interpersonal Style Inventory (ISI), and a 3-day food record prior to, and following, consumption of a caffeine and refined sucrose free diet (experimental group) or a red meat and artificial sweetener free diet (control group). Subjects whose depression ameliorated after eliminating refined sucrose and caffeine completed a 3-month follow-up. The experimental group demonstrated a significantly greater decline in depression on all depression measures and on several measures of general psychopathology at posttest. This amelioration of depression was maintained at a 3-month follow-up.
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