Dietary Total Antioxidant Capacity and Dietary Polyphenol Intake and Prevalence of Metabolic Syndrome in Polish Adults: A Nationwide Study.

Małgorzata Elżbieta Zujko,Wojciech Drygas,Krystyna Kozakiewicz,Tomasz Zdrojewski,Danuta Szcześniewska,Anna Waśkiewicz,Anna Maria Witkowska

doi:10.1155/2018/7487816

Abstract

Specific classes and subclasses of polyphenols have been studied for their potential effects on noncommunicable diseases, but studies on association between dietary polyphenol intake (DPI) and dietary total antioxidant capacity (DTAC) and MetS (metabolic syndrome) are scarce. Therefore, the aim of this study was to determine associations between DTAC and DPI and the prevalence of MetS and its components in the Polish adult population. Subjects (5690) were participants of the Polish National Multicentre Health Examination Survey (WOBASZ II study) performed in 2013-2014. MetS was defined according to the International Diabetes Federation (IDF) and the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) criteria. Daily food consumption was assessed by 24-hour dietary recall. DTAC and DPI were evaluated using the data of food consumption and antioxidant potential of foods, measured by FRAP (ferric reducing antioxidant potential) method, and total polyphenol content in foods, measured by Folin-Ciocalteu assay. Logistic regression models were used to assess the relationship between DTAC and DPI and MetS and its components. Crude, age-adjusted, and multivariable-adjusted models were performed. This study demonstrated that in Polish women, high DPI and high DTAC were significantly associated with a reduced odds ratio for the prevalence of MetS components, such as elevated blood pressure and diabetes. In contrast, in men, high DPI and high DTAC did not have the potential to alleviate MetS components.

Highlights

Metabolic syndrome (MetS) is a clustering of risk factors, such as central obesity, elevated fasting glucose, elevated triglycerides, reduced high-density lipoprotein cholesterol, and elevated blood pressure, that together culminate in the increased risk of diabetes mellitus type 2 (DM2) and cardiovascular disease (CVD)
These have come from the International Diabetes Federation (IDF) and the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) [2]
It was found that MetS criteria have been met by 36% of participants (39% men and 33% women)

Summary

Introduction

Metabolic syndrome (MetS) is a clustering of risk factors, such as central obesity, elevated fasting glucose, elevated triglycerides, reduced high-density lipoprotein cholesterol, and elevated blood pressure, that together culminate in the increased risk of diabetes mellitus type 2 (DM2) and cardiovascular disease (CVD). Various diagnostic criteria have been presented by different organizations. Most recently, these have come from the International Diabetes Federation (IDF) and the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) [2]. The prevalence of MetS varies widely across population and depends on several factors, such as age, gender, socioeconomic status, education level, and lifestyle [3,4,5]. A consequence of metabolic syndrome is CVD and DM2, which are the leading public health problems with high socioeconomic cost. The global cost of diabetes is $825 billion dollars per year [8], while CVD costs US $555 billion per year [9] and €210 billion per year [10]

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