Dietary Sources of Plasma trans Fatty Acids among Adults in the United States: NHANES 2009–2010

Abstract

Intake of trans fatty acids (TFAs) increases LDL cholesterol, decreases HDL cholesterol, and increases the risk of heart disease morbidity and mortality. Many food products potentially contain industrially produced or ruminant TFAs. However, little is known about the dietary sources of plasma TFA concentrations. The objective of this study was to examine associations between foods consumed and plasma TFA concentrations using 24-h dietary recall data and plasma TFA measures among adults aged ≥20 y who participated in the NHANES 2009-2010 in the United States. Over 4400 food products in the dietary interview data were categorized into 32 food and beverage groups/subgroups. Four major plasma TFAs (palmitelaidic acid, elaidic acid, vaccenic acid, linolelaidic acid) and the sum of the 4 TFAs (sumTFAs) were analyzed using GC-MS. Multivariable linear regression analyses were conducted to identify associations of plasma TFAs with all 32 food and beverage groups/subgroups, controlling for the potential confounding effects of 11 demographic, socioeconomic, behavioral, lifestyle, and health-related variables. Consumption of the following food groups/subgroups was significantly associated with elevated plasma TFA concentrations: cream substitutes (P<0.001 for palmitelaidic acid, elaidic acid, vaccenic acid, and sumTFAs); cakes, cookies, pastries, and pies (P<0.001 for elaidic acid, vaccenic acid, and sumTFAs; P<0.05 for linolelaidic acid); milk and milk desserts (P<0.01 for palmitelaidic acid and vaccenic acid; P<0.05 for linolelaidic acid and sumTFAs); beef/veal, lamb/goat, and venison/deer (P<0.01 for vaccenic acid; P<0.05 for sumTFAs); and butters (P<0.001 for palmitelaidic acid and vaccenic acid; P<0.05 for sumTFAs). The findings suggest that the above 5 food groups/subgroups could be the main dietary sources of plasma TFAs among adults in the United States in 2009-2010.