Dietary Risks Assessment of Antibiotic Residues and Microbial Safety of Local Honey in Adamawa State

Abstract

This study investigated the microbial safety and dietary risk assessments of antibiotic residues in honey. The determination of antibiotic residues in this study were carried out using HPLC (LC 1200 series Agilent Tech). The results of the microbial analysis of the honey samples showed that, some of the honey samples were contaminated with micro-organisms. The antibiotics with highest mean concentration in the study were chloramphenicol (6.468±0.03 µg/kg) and sulfonamide (5.553±0.04 µg/kg) from sample HS1 and HG2 respectively. Estimated daily intake (EDIs) of detected antibiotic residues which were compared with the recommended acceptable daily intake (ADIs) for each antibiotic allowed in food. Chloramphenicol was observed to possess the highest risk for adults and children (1.08E-04 µg/kg/bw) and (4.31E-04 µg/kg/bw) respectively in sample HS1. All the EDIs evaluated for antibiotic residues falls below acceptable daily intake (ADI). The target hazard quotient (THQ) and health index (HI) for antibiotic residues in all the samples were < 1, this suggested no risks associated with the level of antibiotic residues risks thus having less danger to human health through its consumption.