Dietary patterns and gastric cancer risk in Mexico (825.3)

Abstract

Objective: To identify the dietary patterns of residents of Mexico City and to assess the association of these patterns with gastric cáncer (GC). Methods: A population based case‐control study with 248 histologically confirmed GC cases and 478 controls paired by age and sex was carried out. The dietary patterns were characterized from 22 food groups through factorial analysis. Results: Three major dietary patterns were identified.pattern 1 was characterized by the consumption of vegetables, fruits and white meat; subjects in the highest quintile of this pattern had a lower GC risk than those in the lowest quintile [Odds Ratio (ORQ5 vs. Q1) = 0.43; 95% Confidence Interval (95%CI): 0.24‐0.77; P‐trend=0.010]. The second pattern included food sources containing simple sugars; a comparison between the extreme quintiles of this pattern resulted in the following: ORQ5vs. Q1 =4.80; 95%CI: 2.56‐8.98; P‐trend<0.001). Conclusión:This is the first study of associations between dietary patterns and GC in Mexico to confirm that GC risk is lower in individuals with healthy dietary patterns.Grant Funding Source: This study was financially supported by CONACYT (Salud‐2002‐001‐7107)