Dietary patterns and colorectal cancer risk in middle-aged adults: A large population-based prospective cohort study

Sangah Shin,Shoichiro Tsugane,H Takaesu,K Kobayashi,Y Furusugi,H Sakiyama,E Maruyama,Taichi Shimazu,Akiko Nanri,N Onga,M Irei,Y Roppongi,Ribeka Takachi,Y Tanaba,Junko Ishihara,Motoki Iwasaki,Norie Sawada,M Urata,I Asano,Eiko Saito,Taiki Yamaji,S Yamato,Manami Inoue,Shizuka Sasazuki,T Minamizono,Takaaki Kondo ,Kazutoshi Nakamura ,Mitsuru Ichii ,Naoyuki Okamoto ,Akira Okayama ,Isao Saito ,Yoshitaka Tsubono ,Suketami Tominaga ,Abdulaziz Seiko ,Tomoko Kadowaki ,Ryohei Sasaki ,Fumitake Saito ,Hiroyasu Iso ,Suminori Akiba ,Keiko Miyakawa ,Hiroki Goto ,Hironori Yamaguchi ,Hisatoyo Yazawa ,Hidehiko Sato ,Yasushi Honda ,Masayuki Akabane ,Tomotaka Sobue ,Tetsuya Mizoue ,Nobufumi Yasuda ,Sei Sato ,Michiyo Yamakawa ,Ryoko Fujita ,F Horii ,Yoshiro Shirai ,Tomoyuki Hanaoka ,Shin‐Ya Nagasawa ,Yujiro Sano ,Masamitsu Konishi ,Atsuhiko Murata ,Fumio Kobayashi ,Naoya Suzuki ,Aya Koizumi ,Yoshinori Ishikawa ,Toru Seo ,Hideaki Suzuki ,Kunihiro Suzuki ,Yusuke Miyagawa ,Mitsuhiko Noda ,Mikio Doi ,Mikio Katagiri ,Yoshimichi Miyajima ,Satoshi Maruyama ,Yoko Kawaguchi ,Shoji Fukushima ,Fuyuaki Ide ,Hironobu Sanada ,Tomoki Ikuta ,Yoshiomi Hatayama ,Kenji Matsui ,Hiroyuki Doi ,Mariko Uehara ,Satoshi Sasaki ,Misao Takano ,Isamu Hashimoto ,Takashi Tagami ,Kazuo Motegi ,Tamaki Fukuyama ,Susumu Sakurai ,Munehito Machida ,Naoyuki Tsuchiya ,Miwa Yamaguchi ,Takeshi Isobe ,Akiko Ioka ,Joice Fabiola Meneguel Ogata ,Toshi Abe ,Yoichi Yoshida ,Yukiyasu Watanabe ,Yutaka Takashima ,Shosui Matsushima ,Toshifumi Mannami ,Masataka Suzuki ,E Takara ,Yoshihiro Kokubo ,Yosuke Matsumura ,Shoko Komatsu ,Haruhiko Sugimura ,Tomoyuki Takashima ,Toshiyuki Nakasone ,Yoritoshi Kobayashi ,Michinori Kabuto ,Fumi Ito ,Kazumasa Yamagishi ,Yoshinori Ito ,Sayumi Watanabe ,Koichi Minato ,Koji Imoto ,H Sueta ,H Uchino ,Nobuyuki Hamajima ,Kunio Aoki ,Ritsuko Saito ,Masakazu Iida ,Hiroyuki Shimizu ,Akira Terao ,Yoshimi Kishimoto ,Naoko Nagai ,Katsutoshi Okada ,Minori Kinjo ,Takeshi Fujieda ,Suminori Kono ,Shinichi Baba ,Wakiko Ajiki ,Manabu Tsukada ,Shusuke Natsukawa ,Yuki Sato

doi:10.1016/j.clnu.2017.04.015

Abstract

A finding between dietary pattern and cancer may provide visions beyond the assessment of individual foods or nutrients. We examined the influence of dietary pattern with colorectal cancer (CRC) among a Japanese population. A total of 93,062 subjects (43,591 men, 49,471 women) who participated in the Japan Public Health Center-based Prospective Study were followed from 1995-1998 to the end of 2012, during which 2482 cases of CRC (1514 men, 968 women) were newly identified. Dietary data was obtained from a validated food-frequency questionnaire between 1995 and 1998. Three dietary pattern was derived from principal components factor: prudent, westernized, and traditional pattern. After controlled for potential confounders, the prudent pattern showed a decreased association of CRC risk in men (HR for highest quintile vs lowest: 0.85; 95% CI: 0.72-1.00; P trend <0.05), slightly more strongly with distal colon cancer (P trend <0.05); but an increased risk of rectal cancer in women (P trend <0.05). The westernized pattern showed a significant positive linear trend for colon (P trend <0.05) and distal cancer (P trend <0.05) in women. There was no apparent association of traditional Japanese dietary pattern on the overall or any specific sites risk of CRC. A prudent dietary pattern showed an inverse association with CRC risk in men, and a westernized pattern was related with a higher risk of colon and distal cancer in women.

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