Dietary Patterns and Bone Health: A NESR Systematic Review

Abstract

Abstract Objectives To inform the 2020–2025 Dietary Guidelines for Americans, USDA and HHS identified important public health questions to be examined by the 2020 Dietary Guidelines Advisory Committee. The Committee conducted a systematic review with support from USDA's Nutrition Evidence Systematic Review (NESR) team to answer the question: What is the relationship between dietary patterns consumed and bone health? Methods The Committee developed protocols that described how they would use NESR's systematic review methodology to examine the evidence. NESR librarians conducted a literature search, and NESR analysts dual-screened the results using pre-defined inclusion and exclusion criteria to identify articles published between 2014 and 2019 that evaluated dietary patterns and bone health, which updates an existing review of evidence from 2000 to 2014. NESR analysts extracted data and assessed risk of bias of included studies. The Committee synthesized the evidence, developed conclusion statements, and graded the strength of the evidence underlying the conclusion statements. Results This systematic review update includes seven prospective cohort studies in adults and two in children, in addition to the thirteen studies included in the existing review. Most studies had few risks of bias, with good consistency, directness, precision and generalizability. Results from studies in adults were consistent in the foods and beverages in the dietary patterns associated with reduced fracture risk. Based on this new evidence in adults, the Committee updated the grade from limited to moderate. Evidence in children remains insufficient. Conclusions Moderate evidence indicates that a dietary pattern higher in fruits, vegetables, legumes, nuts, low-fat dairy, whole grains, and fish, and lower in meats (particularly processed meats), sugar sweetened beverages, and sweets is associated with favorable bone health outcomes in adults, primarily decreased risk of hip fracture. (Grade: Adults – Moderate) Insufficient evidence is available to determine the relationship between dietary patterns consumed during childhood and bone health. (Grade: Children – Grade not assignable) Funding Sources USDA, Food and Nutrition Service, Center for Nutrition Policy and Promotion, Alexandria, VA.