Abstract

Background: There is a paucity of studies that have explored the association between dietary pattern and cognitive function, and whether there is an interaction between dietary pattern and hypertension in relation to older people's cognitive functioning.Methods: We analyzed data from the China Health and Nutrition (CHNS) survey. Dietary data have been collected since 1991, and cognitive function interview data were collected between 1997 and 2006. We analyzed ten years of data, including 4,847 participants with 10,658 observations (aged ≥55 years). Exploratory factor analysis was used to identify dietary patterns. Cognitive function measures include cognitive global scores and verbal memory scores. Linear mixed models were used to investigate the association between dietary patterns, hypertension and cognitive function.Results: Three dietary patterns were identified by factor analysis, named “Traditional Chinese,” “Protein-rich,” and “Starch-rich” dietary pattern. A Protein-rich dietary pattern (high intake of milk, eggs and soymilk) was significantly associated with higher cognitive global scores and verbal memory scores, while the starch-rich dietary pattern (high intake of salted vegetable and legumes) was significantly associated with lower cognitive global and verbal memory scores. In addition, we found that participants with hypertension were independently associated with significant low cognitive function.Conclusion: The study reinforces the importance of diet in preventing cognitive decline among the older population. Identification of older populations who had hypertension should be targeted in intervention studies to maintain their cognitive health.

Highlights

  • As the positive link was found between protein-rich dietary pattern and both cognitive global and verbal memory scores, and the negative link was found for starch-rich dietary pattern and both cognitive global and verbal memory scores, we further examined the association between each food component in these two dietary patterns and the cognitive function after adjusting for sociodemographic and health behavior factors

  • The study identified three dietary patterns: a protein-rich dietary pattern was inversely associated with cognitive decline, while starch-rich dietary pattern was positively associated with cognitive decline for both cognitive global scores and verbal memory scores

  • No interaction was found between hypertension and dietary pattern impacting on cognitive health, but we found hypertension to be an independent factor which is significantly associated with cognitive function among older Chinese population

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Summary

Introduction

It is predicted that the proportion of population aged 60 years and over will increase from 14.3% in 2012 to 25% in 2035, and further increase to 40% in 2040 [1]. This change in age structure has an impact on the increasing incidence of age-associated diseases or conditions, such as cardiovascular disease, arthritis, type 2 diabetes, hypertension, cognitive decline, and dementia [2]. A recent epidemiological study in China showed that 20.1% of people aged 60 or above had MCI, which implies the risk of high prevalence of dementia [9]. There is a paucity of studies that have explored the association between dietary pattern and cognitive function, and whether there is an interaction between dietary pattern and hypertension in relation to older people’s cognitive functioning

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