Abstract
The redox system is essential for maintaining cellular homeostasis. When redox homeostasis is disrupted through an increase of reactive oxygen species or a decrease of antioxidants, oxidative distress occurs resulting in multiple tissue and systemic responses and damage. Poultry, swine and fish, raised in commercial conditions, are exposed to different stressors that can affect their productivity. Some dietary stressors can generate oxidative distress and alter the health status and subsequent productive performance of commercial farm animals. For several years, researchers used different dietary stressors to describe the multiple and detrimental effects of oxidative distress in animals. Some of these dietary challenge models, including oxidized fats and oils, exposure to excess heavy metals, soybean meal, protein or amino acids, and feeding diets contaminated with mycotoxins are discussed in this review. A better understanding of the oxidative distress mechanisms associated with dietary stressors allows for improved understanding and evaluation of feed additives as mitigators of oxidative distress.
Highlights
Redox homeostasis is an essential mechanism for aerobic organisms
This section will focus on three different dietary stressors that might be common and can affect poultry and pig production, including: (1) harmful feed ingredients, such as peroxidized lipids [54], (2) nutrient imbalances, such as heavy metals and amino acid deficiencies, and (3) mycotoxins, which induce the generation of cellular free radicals resulting in redox imbalances at the gut level
The dietary inclusion of oxidized fats and oils, SBM, heavy metals, amino acids, proteins, or mycotoxins may be used as effective models of oxidative distress in poultry, swine and fish
Summary
Redox homeostasis is an essential mechanism for aerobic organisms (bacteria, plants, animals and humans). Animals such as poultry, swine and fish are exposed to several environmental, technological, chemical, and nutritional stressors resulting in potential oxidative distress. Oxidative distress is mitigated by endogenous antioxidants which act to decrease the production of ROS [4]. For these reasons, it is important to better understand. We will discuss (1) the function of ROS in conditions of oxidative eustress and distress, (2) the mechanisms of the endogenous antioxidant system, and (3) the impact of nutritional challenge models on production parameters and biomarkers of oxidative distress in poultry, swine, and fish
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.