Dietary intake of antioxidant nutrients and peripheral plasma determination of T‐BARS in normal weight and obese Mexican people (830.14)

Abstract

The study objective was to evaluate the consumption of antioxidants and the oxidative stress condition in the peripheral compartment of Mexican obese people. The control group (CG) included 52 participants with a BMI of 18.5‐24.9. The overweight (OW) group included 31 participants with BMI of 25‐29.9 and the obesity group (OB) included 64 participants with IMC>30. A standardized antioxidant food frequency survey was applied to assess the intake of antioxidant vitamins A, C, E and the minerals: Cu, Mn, Se and Zn. T‐BARS concentration was assayed in plasma spectrophotometrically. The intake of vitamins, minerals and the T‐BARS concentration were compared with ANOVA of Kruskal‐Wallis between groups; a p<0.05 was accepted as a statistical difference. There were not differences between the consumption of minerals and vitamins between the CG, OW and OB groups. The concentration of T‐BARS in CG, OW and OB were 5.5+/‐3.8 µM, 6.1+/‐5.2 µM and 15.9+/‐8.2 (p<0.05 versus CG), respectively. When OB group was stratified by obesity degrees the concentration of T‐BARS were 14.9+/‐8.9, 15.2+/‐6.7 and 14.8+/‐8.1 for OB‐1 (BMI 30‐34.9), OB‐2 (BMI 35‐39.9) and OB‐3 (BMI>40), respectively. There were no statically differences between stratified OB groups and all of them showed difference (p<0.05) versus CG. The consumption of vitamins and minerals by CG, OW and OB groups showed similar values; however the oxidative stress marker (T‐BARS) in peripheral plasma of OB group showed a robust increase in comparison with CG and OW groups, respectively.Grant Funding Source: Supported by Universidad Iberoamericana Ciudad de Mexico