Abstract
The major protease plays an important role in the development of the virus [ ]screening plant compounds which could inhibit this protease is of importance in new drug discovery Protein The protein selected for molecular docking from corona virus is the main protease 6M03 which is a cysteine protease 6M0310 crystal structure contains 306 amino acids with a molecular mass of 33825 547 Daltons In this study, we have docked the crystal structure of main COVID-19 protease in apo form (PDB ID: 6M03, resolution: 2A) obtained from RSCB protein data bank and the ligands are obtained from PubChem [ ]these two dietary flavonoids could act as competitive inhibitors of SARS-CoV-2 major protease
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