Abstract

Abstract Background Fatty acids are important components of diet that may influence the development of CVD. Objective To verify the relationship of dietary fatty acids with cardiometabolic markers in individuals at the cardiometabolic risk. Methods This cross-sectional study involved 282 subjects (116 M/166 F, 42 ± 16 years) attended the Cardiovascular Health Care Program, Universidade Federal de Vicosa (Brazil). Anthropometric and body composition measurements as well as metabolic and inflammatory markers were assessed by standard procedures. Demographic and lifestyle variables [...]

Highlights

  • Fatty acids are important components of diet that may influence the development of cardiovascular diseases (CVD), since fatty acids participate in important biological functions, such as energy substrate, regulation of metabolic pathways and inflammatory processes, Helen Hermana Miranda Hermsdorff, RD, PhD Associate Professor, Department of Nutrition and Health Universidade Federal de Viçosa - UFV helenhermana@ufv.br

  • The medium chain fatty acids are absorbed in the non-esterified form and transported to the liver, bound to albumin, where they are rapidly metabolized

  • Long-chain fatty acids undergo a process of esterification, forming triglycerides, which can remain in the bloodstream, carried by chylomicrons, or released into the tissues, acting as a form of fat storage in the body

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Summary

Introduction

(DM), dyslipidemias, systemic arterial hypertension and cardiovascular diseases (CVD).[3] In this context, fatty acids are important components of diet that may influence the development of CVD, since fatty acids participate in important biological functions, such as energy substrate, regulation of metabolic pathways and inflammatory processes, Manuscript received April 03, 2019; revised manuscript October 16, 2019; accepted November 24, 2019. Excessive deposition of these lipids may lead to an increase in CVD.[7] little is known about the relationship between the consumption of medium and long chain fatty acids and cardiovascular risk parameters. (Int J Cardiovasc Sci. 2020; 33(5):447-456) Keywords: Cardiovascular Diseases, Risk Factors; Metabolic, Syndrome; Obesity/prevention and control; Fatty, Acids; Biomarkers Conclusion: This cross-sectional study found different associations of dietary fat and cardiometabolic risk related to adiposity and inflammatory markers, according with chain-size and saturation, indicating the need the more detailed on the dietary assessment of obese patients to identify risk factors and established best strategies to control. (Int J Cardiovasc Sci. 2020; 33(5):447-456) Keywords: Cardiovascular Diseases, Risk Factors; Metabolic, Syndrome; Obesity/prevention and control; Fatty, Acids; Biomarkers

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