Dietary fat intake and colorectal adenoma in Korean adults

Abstract

Dietary fat intake has been suggested to be related to risk of colorectal neoplasia. We examined the association between intakes of dietary total, animal and vegetable fats and the prevalence of colorectal adenoma in Korean adults. Study participants were Korean men and women aged 39–73 who underwent colonoscopy at the health examination center at Daegu Catholic University Medical Center in 2006–2012. A total of 933 participants (334 men and 599 women) were included. Participants with adenomatous polyps were included as case group (n = 281), and those without polyps were included as control group (n = 652). We analyzed the associations of intakes of dietary total, animal, and vegetable fats in relation to the prevalence of colorectal adenoma. We calculated odds ratios (ORs) and 95% confidence intervals (CIs) using the multivariate logistic regression model. We observed no associations between intakes of dietary total, animal, and vegetable fats and the prevalence of colorectal adenoma. Comparing the highest quintile with the lowest quintile, multivariate ORs (95% CIs) were 0.73 (0.73–1.17; p for trend = 0.62) for total fat intake, 1.02 (0.64–1.64; p for trend = 0.70) for animal fat intake, and 0.74 (0.47–1.19; p for trend = 0.38) for vegetable fat intake. In conclusion, our data does not support the hypothesis that total, animal or vegetable fat intakes are associated with colorectal adenoma in Korean adults.