Dietary calcium intake in patients with inflammatory bowel disease

Abstract

Background & aimsOsteopenia and increased risk for fractures in IBD result from several factors. Aim of the studyTo investigate the dietary intake of calcium in IBD patients. MethodsA 22-item quantitative validated frequency food questionnaire was used for quantifying dietary calcium in relation to gender and age, in 187 IBD patients, 420 normal- and 276 diseased controls. Statistical analysisMann–Whitney, chi-square- and T-tests. ResultsThe mean calcium intake was 991.0±536.0 (105.8% Recommended Daily Allowances) and 867.6±562.7SDmg/day (93.8% RDA) in healthy and diseased controls, and 837.8±482.0SDmg/day (92.7% RDA) in IBD, P<0.001. Calcium intake was high in celiac disease (1165.7±798.8SDmg/day, 120% RDA), and non-significantly lower in ulcerative colitis than in Crohn's disease (798.7±544.1SDmg/day vs 881.9±433.0). CD and UC females, but not males, had a mean calcium intake well under RDA. In all study groups the intake was lower in patients believing that consumption of lactose-containing food induced symptoms, versus those who did not (105.8% vs 114.3% RDA in normal controls; 100.4% vs 87.6% RDA in IBD). ConclusionsDiet in IBD patients contained significantly less calcium than in healthy controls. Gender and age, more than diagnosis, are central in determining inadequate calcium intake, more so in IBD. Self-reported lactose intolerance, leading to dietary restrictions, is the single major determinant of low calcium intake. Inadequate calcium intake is present in one third of IBD patients and represents a reversible risk factor for osteoporosis, suggesting the need for tailored nutritional advice in IBD.