Abstract

The fact that people born small for gestational age (SGA) have increased risk of having cardiovascular disease is well described. Advances in the care of these infants have resulted in the majority of them surviving into adulthood only to suffer from premature atherosclerosis and elevations in blood pressure. Currently little is known about prevention strategies that may be helpful in reducing this increased risk. Dietary omega-3 fatty acids may be useful in reducing this problem in SGA people as the age but studies to date have been limited by size and design. In this issue of The Journal, Skilton et al report the results of the STRIP study which followed 115 infants who were born SGA and recorded their food records, blood pressure, and aortic intima-media wall thickness every 3-12 months for 19 years. The results suggest that long-term dietary alpha-linolenic acid intake during childhood is associated with improved vascular health and blood pressure in people who are born SGA. The results of this study are promising; however, randomized trials with evaluations of other possible dietary components will be needed before firm conclusions and recommendations can be made. This study is an excellent start. Article page 1252▶ The Association of Dietary Alpha-Linolenic Acid with Blood Pressure and Subclinical Atherosclerosis in People Born Small for Gestational Age: The Special Turku Coronary Risk Factor Intervention Project StudyThe Journal of PediatricsVol. 166Issue 5PreviewTo determine whether dietary alpha-linolenic (omega-3) fatty acid intake is associated with lower blood pressure and aortic intima-media thickness (IMT) in people born small for gestational age (SGA). Full-Text PDF

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