Abstract
In prospective randomized nutritional outcome studies it has been demonstrated that early nutrition, in preterm infants, influences developmental outcome in childhood. Children fed nutrient-enriched formula performed better than those fed standard term formula, even though the assigned diet was fed, on average, for only the first 4 weeks of life. Despite its poorer nutrient content, children fed donor breast milk performed as well as those fed preterm formula, raising the possibility that something in human milk (e.g. biologically active polypeptides or long chain polyunsaturated fatty acids, LCPUFAs) promotes neurodevelopment. Evidence is presented on the role of LCPUFAs and dietary iron in neurodevelopment.
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