Abstract

The baboon is capable of responding to dietary cholesterol with a moderate increase of serum cholesterol within one year. Marked individual variation in this response occurs with animals on identical diets. The level of dietary cholesterol is the only dietary variable (of those investigated) with a major effect on changes in serum cholesterol after 12 months on diet. Fat blends, one made up predominatly of corn oil and another composed principally of beef tallow, butter oil, and hydrogenated vegetable fats, appear to have no main effect on changes in serum cholesterol after 12 months on diet, but there is interaction between dietary cholesterol and type of fat. Dietary protein levels of 8 and 20% of calories appear to have no major effects on changes in serum cholesterol levels.

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