Abstract

Dielectric measurements carried out on phospholipid vesicles about 280 Å in diameter suspended in dilute aqueous salt solution show a dispersion centered at about 40 MHz which is analogous to the “β-dispersion” observed in suspensions of biological cells and organelles. Measurements over a wide frequency range reveal no “α-dispersion”, provided the vesicles have zero net charge. Analysis of the electrical characteristics of the suspension based on the Pauly-Schwan equations gives values of 3.3 to 4.2 μF/cm 2 for the capacitance of the phospholipid shell. The homogeneous suspensions of phospholipid vesicles were prepared from purified egg phosphatidylcholine according to the procedure of Huang 3.

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