Dieldrin, effect on the ion transport activities in liver tissues

Abstract

The results of a survey on the effects of dieldrin upon the rat liver systems showed that this chlorinated hydrocarbon insecticide markedly affects Na(+) and Ca(++) ion transport mechanisms in the liver. Transport mechanisms for other ions appeared to be only moderately affected. The situation resembles that which occurs in the nerve cells under dieldrin influencein vivo (7). The eventual results of such a physiological modification is excitation of liver cells due to the effect of accumulated sodium and depletion of calcium ions.