Die Verteilungsmechanismen von β-barrel-Proteinen in Pflanzenzellen

Abstract

Mitochondria and plastids contain nuclear encoded β-barrel proteins in their outer membranes required for the exchange of metabolites and solutes. The specificity of the outer membrane proteome of the two organelles calls for targeting mechanisms discriminating between them. In vivo approaches based on self-assembling green fluorescent protein (GFP) define the highly hydrophobic last β-hairpin serving as signal for β-barrel protein targeting to mitochondria and maybe as “bouncing off” signal for plastids.