Abstract
Sensory photoreceptors underpin diverse adaptive responses in nature and serve as genetically encoded, light-gated actuators in optogenetics. Photoactivated nucleotide cyclases (PACs) enable light-dependent control over the formation of cyclic nucleotides (cNMPs). Conversely, the engineered, red-light-activated phosphodiesterase LAPD mediates the hydrolytic breakdown of cNMPs. In combination, PACs and LAPD hence unlock precise and graded control over intracellular cNMPs and associated processes.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Biospektrum : Zeitschrift der Gesellschaft fur Biologishe Chemie (GBCH) und der Vereinigung fur Allgemeine und Angewandte Mikrobiologie (VAAM)
Paper Title
Journal
Date
