Abstract
100 stool extracts from patients with poliomyelitis or from individuals after oral poliomyelitis vaccination were inoculated simultaneously into HeLa, monkey kidney, and human thyroid cultures. In most cases (88 times) a cytopathic effect was seen in all three cultures. Failures were most frequently encountered in thyroid, rarely in monkey kidney cells. They were due either to thyroid culture lots with reduced viral susceptibility or to small amounts of virus in the stool specimens. No qualitative difference was found in the host range of individual virus strains. With attenuated viruses the cytopathic effect in HeLa cells as a rule was delayed for several days.
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