Abstract

The filoviruses Ebolavirus (EBOV) and Marburgvirus cause fatal hemorrhagic fevers in humans and other mammals, known as Ebola virus disease (EVD), with mortality rates approaching 90% [1] which makes it listed as world health organization risk group 4 pathogen. Ebola virus caused the 2013–2015 epidemic in West Africa, which has resulted in at least 9,268 confirmed deaths and 23,034 suspected cases as of 18 Feb 2015 [2]. Consequently, considerable effort is focused on developing therapeutics and vaccines to prevent infections.

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