Abstract
IN a survey of the embryological evidence of one-egg twinning in man, Corner1 has classified one-egg twins according to their time of separation, as follows : (1) Separation of early blastomeres inside the zona pellucida. Each then develops its own blastocyst, the two becoming completely separate on dissolution of the zona, and implanting separately in the same way as two-egg twins. (2) Duplication of the inner cell mass in a single blastocyst. The two embryos implant together ; but their amnia and placentae are separate. (3) A single inner cell mass differentiates two primitive streaks. The embryos will have a common amnion. Imperfect duplication of the primitive streaks will give all stages from Siamese twins to two-headed monsters.
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