Abstract
AbstractEnantiomerically enriched 1‐[2‐(1‐hydroxyalkyl)cycloalkylidene]methyl N,N‐diisopropylcarbamates, which are easily available by an asymmetric homoaldol reaction, condense with aldehydes under the influence of boron trifluoride etherate to form cyclohexano‐ or cyclopentano‐annulated tetrahydrofuran‐3‐carboxaldehydes, bearing two quaternary carbon atoms and four adjacent stereogenic centers, with complete diastereoselectivity.
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