Abstract
A method for the investigation of diastereoselective effects in reactions of gaseous ions bearing flexible backbones is described. It relies on the study of diastereoselectively labeled substrates that are studied by contemporary mass spectrometric means. While most examples discussed here deal with bond activations mediated by bare transition-metal ions in the gas phase, it is shown that the method is not restricted to this particular chemistry. Interestingly, the reason why transition-metal ions show relatively pronounced diastereoselective effects is that the activation barriers associated with their reactions are sufficiently small to be influenced by even subtle steric modifications of the substrate. Provided that suitable isotopically labeled precursors are investigated, even complex mechanistic schemes including competing side reactions can be analyzed by kinetic modeling of the isotope distributions in the reaction products.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
