Abstract
Abstract A nickel-catalyzed three-component coupling of 1,3-diene, ketone, and organoboron or organosilicon reagents was investigated. While the coupling reaction using PhB(OH)2 afforded a 1,3-syn-substituted 4-penten-1-ol derivative as a single diastereomer, the reaction in the presence of tetraorganosilicon reagent under similar conditions exclusively produced the corresponding 1,3-anti isomer. In both reactions, a tetrasubstituted carbon center was constructed in a highly diastereoselective manner.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
