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Abstract
Abstract The nucleophilic addition of organotitanium reagents to α-keto amides derived from (2R,5R)-trans-2,5-bis(t-butyldimethylsiloxymethylsiloxymethyl)pyrrolidine [(R,R)-BTBSP] afforded the corresponding α-hydroxy amides with very high diastereofacial selectivity.
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