Abstract

ABSTRACTAn efficient three-component synthesis of 2-amino-1,4,5,6-tetrahydro-pyrano[3, 2-c]quinolin-5-one derivatives via a reaction between 4-hydroxyquinolin-2(1H)-one, aromatic aldehydes, and malononitrile/ethyl cyanoacetate using diammonium hydrogen phosphate as catalyst was described. Mild conditions, short reaction time, good to excellent yields, cheap and easily available catalyst, reusability of catalyst and reaction media, and easy work-up are the key features of this method.

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