Abstract

Liposclerosing myxofibrous tumor of bone is a benign lesion with a complex histologic structure. Its origin is uncertain, although it seems to be related to intraosseous lipomas and fibrous dysplasia, and it is sometimes impossible to distinguish from these two entities. It is usually located in the intertrochanteric region of the femur. Radiologically, it is a well-defined lytic lesion with sclerotic margins and high signal intensity in T2- weighted MR images. We present two cases with radiologic characteristics and location compatible with liposclerosing myxofibrous tumor of bone. In one case, PET studies suggested a malignant lesion. The diagnosis can be established on the basis of the radiological characteristics and location of the lesion: PET and histologic examination can sometimes lead to the wrong diagnosis.

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