Abstract
IntroductionInfertility caused by genetic factors affect a large number of couples seeking treatment assisted human reproduction. The preimplantation genetic diagnosis (PGD) is a technique used during assisted human reproduction that investigates chromosomal and genetic abnormalities in vitro embryos during different stages of development and select genetic healf embryos to the uterine implantation. Three types of biopsy may be performed in PGD: biopsy of polar cells, biopsy of blastomere and biopsy of the blastocyst in chronological order according to embryonic development. Objectiveto analyze the applicability and relevance of the PGD technique on human assisted reproduction laboratory routine and review its methodology. MethodThis article provides an overview on the technical and ethical issues involved with PGD. ResultsMany studies suggest that there is currently no detrimental effects on embryos that underwent biopsy. PGD in Brazil is seen as a tool to aid in the assisted human reproduction and presents ethical issues still under discussion. ConclusionsThe PGD respects the vision and values of the society that considers health as one of its greatest assets.
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