Diagnostik der Meta-bolischen Dysfunktion- assoziierten Steato- hepatitis (MASH)

Abstract

This 2nd part of the review on the diagnosis and care of patients with of patients with metabolically associated steatohepatitis (MASH) addresses the challenges the challenges and recommendations in consideration of the current S2k guidelines. The diagnostic algorithm focusses on on a screening procedure for the early detection of MASH, with general practitioners are key players. In the event of elevated liver values or an abnormal Fatty Liver index, further examinations and, if necessary, referral to a specialist are are planned. Particularly for risk groups such as people with type 2 diabetes, obesity obesity or metabolic syndrome, early identification is essential, to be able to take preventive action. Comprehensive metabolic diagnostics is a is a prerequisite for preventing the progression of the disease. However, the care situation in the diagnosis of MASH is characterised by a number of characterised by a number of limitations, including the limited use of the of the screening algorithm and the challenges involved in making a definitive diagnosis by means of liver biopsy. The discrepancy between the diagnosed number of MASH cases diagnosed and the presumed prevalence indicates a significant significant number of undiagnosed cases, which ultimately also leads to therapeutic deficit