Abstract

Clear cell odontogenic carcinoma (CCOC) is an aggressive odontogenic tumor with distinctive behavior. Woman, 27, had an asymptomatic swelling on the left side of the mandible of 3 months' duration. Intraorally the lesion showed lingual-vestibular expansion but no mucosal ulceration. Orthopantomography showed an osteolytic radiolucence in the molar area extending to the anterior region. Samples from an incisional biopsy analyzed histologically showed malignant epithelial islands rich in clear cells in a collagenous and hyaline stroma, considered to be carcinoma.

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