Diagnostic Value of Thromboelastography for Acute Disseminated Intravascular Coagulation

Abstract

To investigate the diagnostic value of thromboelastography(TEG) for acute disseminated intravascular coagulation(DIC). The clinical data and data of blood routine indexes, blood coagulation indexes and TEG indexes of acute 155 DIC patients were collected and analyzed retrospectively. The CDSS scores of DIC and non-DIC groups were 9.2±1.4 and 4.2±1.1 respectively, and the CDSS scores of DIC group was significantly higher than those in non-DIC group(P＜0.05). The PLT level in DIC group was significantly lower than that in non-DIC group(P＜0.05), the PT, APTT, INT, DD and FIB levels in DIC group were significantly higher than those in non-DIC group(P＜0.05). The R time, K time and LY30 in DIC group were significantly higher than those in non-DIC group(P＜0.05), and the α and MA in DIC group were significantly lower than those in non-DIC group(P＜0.05). ROC curve analysis showed that the best cutoff value of R time, K time, α, MA and LY30 were 8.4 min, 6.2 min, 52.5°, 43.2 mm and 6.7% respectively. The AUC of total scores≥1, ≥2, ≥3 and ≥4 were 0.552, 0.650, 0.687 and 0.613 respectively. The TEG possesses the certain value in the diagnosing of DIC.